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. 2020 Aug 10;38(3):281–290. doi: 10.1080/02813432.2020.1802140

Table 9.

Systematic review of the association between T2D and DST and changes of cognition.

Authors T2D at intake
N (%)
Cognitive test Cognitive status
Mean (SE)
Cognitive changes
Mean (SE)
Non-DM DM p Value Non-DM DM p Value
Espeland et al. [16] 179 (8.3%) Digit Span Forward
Digit Span Backward
7.45 (2.09)
6.67 (2.02)
7.33 (1.87)
6.72 (2.09)
0.45
0.73
Change in cognition adjusted for all risk factors, attention/working memory 0.04 (0.07) p 0.56
Hassing et al. [21] 36 (13.1%) Digit Span Forward
Digit Span Backward
5.5 ± 1.2
3.5 ± 1.6
5.5 +/. 1.4
3.5 ± 1.2
  −0.10 (0.2)
−0.11 (0.02)
−0.02 (0.04)
−0.08 (0.05)
<0.05
<0.05
Logroscino et al. [17] 1394 (7.3%) Digit span Backwards 6.7 (2.4) 6.4 (2.4)   The change was reported in global cognition score