Table 3.
Risk factors for therapy failure, recurrence and complications.
| Therapy failure n = 192 |
Recurrence n = 1277 |
Complication n = 121 |
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|---|---|---|---|---|---|---|
| Crude OR (95% CI) | Adjusteda OR (95% CI) | Crude OR (95% CI) | Adjusteda OR (95% CI) | Crude OR (95% CI) | Adjusteda OR (95% CI) | |
| Age over 55 years | 1.6 (1.1–2.3) | 1.6 (1.2–2.3) | 1.6 (1.4–1.9) | 1.7 (1.5–2.0) | 1.9 (1.2–2.9) | 1.7 (1.1–2.7) |
| CRP ≥20 mg/L | 1.1 (0.8–1.5) | 1.4 (1.0–1.9) | 0.7 (0.6–0.9) | 1.0 (0.9–1.2) | 2.7 (1.9–3.9) | 2.8 (1.9–4.1) |
| Broad-spectrum antibiotic ≥10 days | Ref | Ref | Ref | Ref | Ref | Ref |
| Broad-spectrum antibiotic <10 days | 1.8 (1.0–3.4) | 1.9 (1.0–3.7) | 1.8 (1.4–2.4) | 1.9 (1.4–2.5) | 0.7 (0.3–1.9) | 0.9 (0.3–2.5) |
| Narrow-spectrum antibiotic <10 days | 1.8 (1.4–2.5) | 2.0 (1.5–2.8) | 2.6 (2.3–3.0) | 2.7 (2.4–3.1) | 0.9 (0.6–1.3) | 1.2 (0.8–1.8) |
CI: confidence interval; OR: odds ratio; CRP: C-reactive protein; Narrow-spectrum antibiotic treatment, pivmecillinam or nitrofurantoin; Broad-spectrum antibiotic treatment <10 days, trimethoprim; Broad-spectrum antibiotic treatment ≥ 10 days, trimethoprim/sulfamethoxazole or ciprofloxacin. Missing cases, CRP 12,345 (58.4%).
a
Method: Log regression enter, adjusted for age, CRP, narrow-spectrum antibiotic, broad-spectrum antibiotic <10 days and broad-spectrum antibiotic ≥10 days. Broad-spectrum antibiotic ≥10 days was used as reference.