Table 3.
Laboratory findings of HD patients infected with COVID-19 on admission to hospital.
| Patients (n = 31) |
||||
|---|---|---|---|---|
| Blood routine | Baseline | Infection | 统计量 | p value |
| Leukocyte count (×109 per L; normal range 3.5–9.5) | 6.3 ± 2.4 | 5.4 ± 2.2 | 1.424 | .165 |
| Increased | 1 (3.2) | 1 (3.2) | ||
| Decreased | 0 | 5 (16.1) | ||
| Neutrophils count (×109 per L; normal range 1.8–6.3) | 4.6 ± 1.9 | 4 ± 1.9 | 1.207 | .237 |
| Increased | 2 (6.5) | 4 (12.9) | ||
| Decreased | 0 | 3 (9.7) | ||
| Lymphocytes count (×109 per L; normal range 1.1–3.2) | 1.1 ± 0.4 | 0.8 ± 0.3 | 2.407 | .022* |
| Increased | 0 | 0 | ||
| Decreased | 16 (51.6) | 25 (80.6) | ||
| Neutrophils/lymphocytes ratios (n/L ratio) | 4.3 (3.7–5.1) | 4.9 (3.2–6.6) | –1.117 | .264 |
| Platelets (×109 per L; normal range 125.0–350.0) | 170.4 ± 55.5 | 198.6 ± 92.3 | –1.515 | .14 |
| Increased | 0 | 3 (9.7) | ||
| Decreased | 7 (22.6) | 8 (25.8) | ||
| Hemoglobin (g/L; normal range 115.0–150.0) | 97.6 ± 15.7 | 92.4 ± 18.9 | 1.074 | .291 |
| Decreased | 28 (90.3) | 27 (87.1) | ||
| Coagulation function | ||||
| D-dimer (µg/L; normal range 0.0–0.55) | 0.3 (0.27–0.49) | 1.8 (1.1–3.4) | –4.464 | <.001** |
| Increased | 9 (29) | 30 (96.8) | ||
| Blood biochemistry | ||||
| Albumin (g/L; normal range 40.0–55.0) | 38.3 ± 2.1 | 33.4 ± 4.1 | 5.965 | <.001** |
| Decreased | 24 (77.4) | 29 (93.5) | ||
| Alanine aminotransferase (U/L; normal range 9.0–50.0) | 10 (8–15.5) | 10 (7–15.5) | –0.228 | .82 |
| Increased | 2 (6.5) | 2 (6.5) | ||
| Aspartate aminotransferase (U/L; normal range15.0–40.0) | 13 (9–17) | 19 (14–23) | –2.224 | .026 |
| Increased | 1 (3.2) | 1 (3.2) | ||
| Total bilirubin (μmol/L; normal range 0.0–21.0) | 6.3 (4.7–7.4) | 5.9 (4.5–7.2) | –1.261 | .217 |
| Increased | 0 | 2 (6.5) | ||
| Blood calcium (mmol/L; normal range 2.11–2.52) | 2.1 ± 0.3 | 2.2 ± 0.2 | –1.179 | .247 |
| Increased | 1 (3.2) | 1 (3.2) | ||
| Decreased | 16 (51.6) | 13 (41.9) | ||
| Blood phosphorus (mmol/L; normal range 0.97–1.6) | 1.7 ± 0.5 | 2.3 ± 1 | –2.473 | .019* |
| Increased | 18 (58.1) | 27 (87.1) | ||
| Decreased | 0 | 1 (3.2) | ||
| Blood urea nitrogen (mmol/L; normal range 3.6–9.5) | 24.5 ± 5.7 | 28.4 ± 17 | –1.304 | .202 |
| Increased | 31 (100) | 30 (96.8) | ||
| Decreased | 0 | 0 (0) | ||
| Serum creatinine (μmol/L; normal range 57.0–111.0) | 968.2 (774.5–1058.4) | 903.5 (807.9–1282.2) | –0.451 | .652 |
| Increased | 31 (100) | 31 (100) | ||
| Decreased | 0 | 0 | ||
| Creatine kinase (U/L; normal range 50.0–310.0) | 92 (63–116.5) | 72 (47.5–116) | –0.941 | .347 |
| Increased | 1 (3.2) | 2 (6.5) | ||
| Decreased | 3 (9.7) | 9 (29) | ||
| Lactate dehydrogenase (U/L; normal range 120.0–250.0) | 193 (165.5–221) | 274 (245.5–297) | –4.057 | <.001** |
| Increased | 2 (6.5) | 21 (67.7) | ||
| Glucose (mmol/L; normal range 3.9–6.1) | 7.79 (6–12.2) | 5.2 (4.7–6) | –2.91 | .004** |
| Increased | 22 (71) | 8 (25.8) | ||
| Decreased | 1 (3.2) | 1 (3.2) | ||
| Infection-related biomarkers | ||||
| C-reactive protein (mg/L; normal range 0.0–5.0) | 2.5 (1.3–4.6) | 35 (19.5–59.6) | –4.494 | <.001** |
| Increased | 7 (22.6) | 28 (90.3) | ||
*
p < .05.
**
p < .01.