Table 4.
The particle size, PDI, and zeta potential of prepared BRU-loaded PLGA NPs:.
| Formulation | Particle
size (nm ± SD) |
PDI | Zeta potential (mV ± SD) | Formulation | Particle
size (nm ± SD) |
PDI | Zeta potential (mV ± SD) |
|---|---|---|---|---|---|---|---|
| NNP1 | 199 ± 3.0 | 0.337 | −16.6 ± 1.7 | NP1 | 215 ± 4.1 | 0.423 | 2.42 ± 0.37 |
| NNP2 | 204 ± 8.1 | 0.542 | −19.7 ± 3.0 | NP2 | 238 ± 3.6 | 0.318 | 1.09 ± 0.15 |
| NNP3 | 206 ± 7.7 | 0.297 | −22.8 ± 2.3 | NP3 | 253 ± 8.7 | 0.368 | 1.79 ± 0.83 |
| NNP4 | 110 ± 2.08 | 0.211 | −23.3 ± 5.2 | NP4 | 124 ± 0.57 | 0.210 | 1.36 ± 0.12 |
| NNP5 | 110 ± 1.0 | 0.192 | −24.2 ± 5.5 | NP5 | 134 ± 0.57 | 0.257 | 2.41 ± 0.11 |
| NNP6 | 121 ± 0.0 | 0.380 | −25.4 ± 2.1 | NP6 | 161 ± 4.5 | 0.378 | 2.17 ± 0.57 |
| NNP7 | 65 ± 4.0 | 0.410 | −24.6 ± 4.5 | NP7 | 94 ± 3.05 | 0.340 | 2.64 ± 0.11 |
| NNP8 | 93 ± 2.8 | 0.320 | −25.5 ± 2.0 | NP8 | 113 ± 0.57 | 0.232 | 3.23 ± 0.62 |
| NNP9 | 98 ± 5.03 | 0.450 | −31.1 ± 7.2 | NP9 | 115 ± 1.15 | 0.390 | 3.71 ± 0.44 |
Values are expressed as mean ± standard deviation (SD) n = 3 and were analyzed by Student’s t-test. All PEG NP formulations p < .05 compared to their naked counterpart.