Table 5.
Entrapment efficiency and % yield of BRU-loaded PLGA NPs:.
| Formulation | Entrapment efficiency % ± SD | Yield % ± SD | Formulation | Entrapment efficiency % ± SD | Yield % ± SD |
|---|---|---|---|---|---|
| NNP1 | 69.1 ± 2.1 | 87.8 ± 1.6 | NP1 | 71.7 ± 1.4 | 89.3 ± 1.1 |
| NNP2 | 70.6 ± 0.9 | 90.7 ± 3.7 | NP2 | 73.2 ± 1.9 | 92.3 ± 1.8 |
| NNP3 | 74.0 ± 2.5 | 92.9 ± 1.5 | NP3 | 77 ± 1.3 | 94.5 ± 1.1 |
| NNP4 | 49.9 ± 1.5 | 82.4 ± 3.4 | NP4 | 52.5 ± 1.6 | 83.8 ± 1.5 |
| NNP5 | 52.3 ± 2.4 | 83.2 ± 2.9 | NP5 | 54.2 ± 1.1 | 84.6 ± 1.2 |
| NNP6 | 59.6 ± 3.4 | 86.1 ± 2.6 | NP6 | 58 ± 1.5 | 85.3 ± 1 |
| NNP7 | 39.1 ± 1.9 | 69.6 ± 0.6 | NP7 | 37.5 ± 1.8 | 70.8 ± 1.4 |
| NNP8 | 40.1 ± 2.1 | 74.2 ± 2.9 | NP8 | 39.1 ± 1.5 | 75.4 ± 1 |
| NNP9 | 41.9 ± 1.4 | 80.0 ± 3.7 | NP9 | 41.1 ± 1.1 | 79.3 ± 1.4 |
Values are expressed as mean ± standard deviation (SD), n = 3 and were analyzed by Student’s t-test, p < .05.