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β-Catenin blockade induces lymphocyte infiltration in MC38-S33Y.β-cat tumors. Mice bearing MC38-S33Y.β-cat tumors were treated with iCRT14 or vehicle every other day for 12 d. Immunofluorescence was performed to analyze tumor-infiltrating CD4+ T (by CD4 staining) (a), CD8+ T (by CD8 staining) (b), and NK cells (by NKp46 staining) (c). Total cell number was counted by nucleus staining (DAPI). Scale bar = 100 µm. ** P < .01, *** P < .001
