Table 1. Characteristics of patients with renal hyperfiltration (RHF).
No RHF (N = 54,481) | RHF(N = 1,511) | P | |
---|---|---|---|
Age (years) | 46.8±12.4 | 46.2±12.7 | 0.040 |
Men (%) | 28,587 (52.5) | 765 (50.6) | 0.157 |
BMI (kg/m2) | <0.001 | ||
<20 | 6,322 (11.6) | 245 (16.4) | |
20–24 | 29,729 (54.7) | 776 (52.1) | |
25–29 | 16,177 (29.8) | 394 (26.4) | |
≥30 | 2,143 (3.9) | 75 (5.0) | |
SBP (mmHg) | 115.7±14.0 | 115.0±15.3 | 0.064 |
≥130 | 11,450 (21.0) | 371 (24.6) | 0.001 |
eGFR (ml/min/1.73m2) | 86.5±13.7 | 126.5±14.1 | <0.001 |
BUN (mg/dL) | 13.1±3.7 | 11.6±3.3 | <0.001 |
Proteinuria (%) | 3,120 (5.8) | 114 (7.6) | 0.003 |
Hematuria (%) | 4,428 (8.2) | 127 (8.4) | 0.716 |
Hb (g/dL) | 14.3±1.6 | 13.9±1.7 | <0.001 |
WBC (/mm3) | 5.99±2.05 | 6.04±1.78 | 0.286 |
Monocyte count (/mm3) | 0.40±0.15 | 0.43±0.17 | <0.001 |
ESR (mm/hr) | 8.4±8.2 | 10.5±11.6 | <0.001 |
CRP (mg/L) | 1.7±5.4 | 2.6±10.3 | 0.006 |
AST (IU/L) | 25.1±17.2 | 28.7±34.2 | <0.001 |
ALT(IU/L) | 25.5±25.1 | 28.0±24.8 | <0.001 |
ALP(IU/L) | 59.5±20.2 | 67.1±27.8 | <0.001 |
GGT(IU/L) | 36.6±55.0 | 47.4±98.0 | <0.001 |
Bilirubin (mg/dL) | 0.8±0.4 | 0.8±0.5 | 0.682 |
FBS (mg/dL) | 95.6±20.8 | 101.2±32.0 | <0.001 |
Albumin (g/dL) | 4.5±0.3 | 4.4±0.3 | <0.001 |
Triglyceride (mg/dL) | 129.7±91.6 | 129.1±105.2 | 0.818 |
HDL cholesterol (mg/dL) | 52.7±12.8 | 51.6±12.9 | 0.001 |
HTN (%) | 8,802 (16.2) | 255 (16.9) | 0.456 |
DM (%) | 3,219 (5.9) | 164 (10.9) | <0.001 |
CAD (%) | 1,840 (3.4) | 38 (2.5) | 0.066 |
Cancer (%) | 2,759 (5.1) | 71 (4.7) | 0.523 |
BMI, body mass index; SBP, systolic blood pressure; eGFR, estimated glomerular filtration rate; BUN, blood urea nitrogen; Hb, hemoglobin; WBC, white blood cell; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; AST, aspartate transaminase; ALT, aspartate aminotransferase; ALP, alkaline phosphatase; GGT, gamma-glutamyltransferase; FBS, fasting blood sugar; HDL, high density lipoprotein; hypertension, HTN; diabetes mellitus, DM; CAD, coronary artery disease.