Table 2. Univariate logistic regression analysis of studied bovine EDN2 variants and independent factors associated with pTB cases and controls.
| SNP | Genotype | Phenotype frequency | Nominal p-value | Adjusted p-valuea | Fixed factors | OR (95% CI) | ||
|---|---|---|---|---|---|---|---|---|
| Case (%) | Control (%) | Sex | Breed | |||||
| rs110287192 | TT | 2 (3.70) | 52 (96.3) | 0.013 | NS | * | 1.00 | |
| TG | 58 (12.53) | 405 (87.47) | * | 0.53 (0.12–2.37) | ||||
| GG | 8 (2.87) | 271 (97.13) | 1.73 (0.34–8.59) | |||||
| rs109651404 | GG | 31 (9.6) | 292 (90.4) | 0.99 | NS | ** | 1.00 | |
| GA | 30 (2.33) | 311 (91.2) | NS | 0.98 (0.32–2.97) | ||||
| AA | 7 (6.67) | 98 (93.33) | 0.76 (0.18–3.16) | |||||
| rs136707411 | GG | 25 (19.23) | 105 (80.77) | 0.023 | NS | ** | 1.00 | |
| GA | 32 (9.42) | 298 (90.58) | NS | 1.66 (0.92–2.98) | ||||
| AA | 11 (3.78) | 280 (96.22) | 2.94 (1.34–6.46) | |||||
Abbreviations: OR: odds ratio; 95% CI: 95% confidence interval
* p ≤ 0.05 indicates statistical significance
** p ≤ 0.01 indicates statistical significance
ap- value was adjusted by Bonferroni correction; NS: not significant p > 0.05