Table 4. Recovery of adult L. loa from RAG2-/-IL-2γc-/- mice infected with L3 derived from experimental injections of C. silacea.
| L3 Source |
Total L3 inoculated |
Mice N |
Site of parasite recovery (% total recovered) |
Total adult L. loa recovered (% L3 inoculate) |
Median adult L. loa recovererd / mouse % L3 inoculate (IR)* |
|||
|---|---|---|---|---|---|---|---|---|
| Sub- Cut. |
muscle | Peritonea | Pleura | |||||
| Head | 489 |
5 | 28 (33.3) | 44 (52.4) | 3 (3.6) |
9 (10.7) | 84 (17.2) |
20.8 (1.8–22.2) |
| Abdomen | 565 |
6 | 21 (45.7) | 19 (41.3) | 5 (10.9) |
1 (2.2) |
46 (8.1) |
7.5 (5.5–10.1) |
| Thorax | 123 |
1 | 2 (16.7) |
9 (75) |
1 (8.3) |
0 (0) |
12 (9.8) |
9.8 |
| Thorax + Abdomen | 472 |
6 | 15 (48.4) | 15 (48.4) | 1 (3.2) |
0 (0) |
31 (6.6) |
4.7 (2.2–10.9) |
| All tissues | 1649 | 18 | 66* (38.2) |
87 (50.3) |
10 (5.8) |
10 (5.8) |
173 (10.5) |
7.5 (3.3–12.9) |
Infective larvae of 50–140 were inoculated per mice depending on recovery from fly anatomical regions
*X2 = 33.8, P<0.001, proportion of adults parasitizing specific tissues