Table 2. Estimated odds ratio (OR) for EwS rare variants adjusting for different model covariates.

		Wald method (unadjusted)		Mantel-Haenszel (study)		Mantel-Haenszel (study and variant1)
Rare SNP	Common SNP	OR (95% CI)	Fisher’s P-value	OR (95% CI)	P-value	OR (95% CI)	P-value
rs112837127	rs6106336	0.19 (0.10 to 0.39)	1.64×10−8	0.18 (0.08 to 0.37)	6.90×10−9	0.20 (0.09 to 0.40)	5.84×10−8
rs2296730	rs6106336, rs6047482	2.04 (1.58 to 2.69)	9.78×10−9	2.11 (1.60 to 2.77)	4.92×10−8	1.61 (1.16 to 2.24)	3.50×10−3

Models use a dominant allele coding for minor alleles with each individual as the analysis unit.

¹Adjustment for contributing study and nearby common SNP(s).