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. 2020 Aug 5;103(3):1220–1222. doi: 10.4269/ajtmh.20-0676

Table 1.

Interpretation of dengue diagnostic test results among patients with COVID-19

Patients (N = 42) RT-PCR/NS1 antigen IgM RDT or ELISA IgG RDT IgG ELISA Interpretation
2 NS1 negative Negative Negative Negative Never infected by DENV
33* NS1 negative Negative Negative Positive Past infection by DENV
4 RT-PCR and NS1 negative Positive (no follow-up IV increase) Negative Positive Recent secondary DENV infection
#1: 4.8 to 4.1 #1: 9.5 to 9.2
#2: 2.8 to 0.5 #2: 8.5 to 8.1
#3: 1.6 to 0.8 #3: 4.8 to 6.4
#4: 3.7 to 1.6 #4: 10.2 to 9.5
3 RT-PCR and NS1 negative Positive (no follow-up IV increase) Positive faint Positive Very recent secondary DENV infection, with high-titer IgG
#1: 3.8 to 3.8 #1: 17.1 to 16.6
#2: 2.5 to 1.1 #2: 12.3 to 11.5
#3: 1.6 to 1.5 #3: 12.5 to 12.3

DENV = dengue virus; IV = index value; RDT = rapid diagnostic test.

*

Ten patients in this group did not have follow-up sera. For patients with positive IgM and IgG, admission and follow-up IV are shown. Changes in both IgM and IgG interpretation were not noted in follow-up sera. There were no cases of current dengue coinfection.