Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Sep 3;11(1):12. doi: 10.1186/s13317-020-00134-0

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 1 — Comparison of ANA detection by IIFA with cutoff 1:80 or 1:160 versus screening for connective tissue disease-specific antibodies by EliA CTD (Thermofisher) screen. The figure shows the results of a simulation of the total number of positive test results as well as the true positive and false negative test results as a function of the prevalence (of connective tissue disease) for three different approaches/methods (screening for ANA by IIFA with cutoff 1:80 and cutoff 1:160 and screening for connective tissue-specific antibodies by EliA CTD Screen). The simulation is based on testing 1000 patients and the performance characteristics are from a recent meta-analysis [33]