Table 10.
Demographic and CSF findings in MOG-EM stratified according to OCB status
| OCB+ patients (at least once positive) | OCB– patients (never positive) | |||
| Sex (m:f) | Patients | 1:1.5 | 1:1.5 | |
| Origin (non-Caucasion:Caucasian) | Patients | 1:14 | 1:11 | |
| Median age at first OCB+ LP | Years | 34 | 38 | |
| Median disease duration at first OCB+ LP | Months | 0 (0-16) | 0 (0-489) | |
| OCB+ all samples | OCB− all samples | |||
| Pleocytosis | Samples | 13/19 (68.4%) | 57/128 (44.5%) | p = n.s. |
| WCC | Samples | 14 (0-151) | 4 (0-463) | p = n.s. |
| WCC > 150 | Samples | 1/18 (5.6%) | 9/128 (7%) | p = n.s. |
| Granulocytes | Samples | 3/10 (30%) | 26/62 (41.9%) | p = n.s. |
| QAlb > Qlim(Alb) | Samples | 11/17 (64.7%) | 51/117 (43.6%) | p = n.s. |
| CSF TP elevated | Samples | 8/18 (44.4%) | 50/122 (41%) | p = n.s. |
| CSF l-lactate elevated | Samples | 3/12 (25%) | 22/91 (24.2%) | p = n.s. |
| Treated at the time of OCB testing | Samples | 10/20 (50%) | 48/131 (36.6%) | p = n.s. |
| Time since attack onset | Days | 14 | 12.5 | |
IgG-IF intrathecal IgG fraction; OCB oligoclonal bands; QAlb CSF/serum albumin quotient; TP total protein; WCC white cell count