Table 9.
CSF findings in samples from patients with monophasic disease and from patients with relapsing disease
| 1st LP/event | Units | Monophasic | Relapsing |
|---|---|---|---|
| Pleocytosis, acute attacks | Samples | 17/27 (63%) | 37/74 (50%)§ |
| Pleocytosis, acute MY | Samples | 12/14 (85.7%) | 20/26 (76.9%) |
| Pleocytosis, acute ON | Samples | 3/9 (33.3%) | 12/40 (30%) |
| Pleocytosis, acute BRAIN | Samples | 2/4 (50%) | 4/6 (66.7%) |
| OCB, acute attacks | Samples | 4/25 (16%) | 5/70 (7.1%)§ |
| OCB, acute MY | Samples | 1/12 (8.3%) | 2/25 (8%) |
| OCB, acute ON | Samples | 1/9 (11.1%) | 2/38 (5.3%) |
| OCB, acute BRAIN | Samples | 2/4 (50%) | 0/6 (0%) |
| IgG-IF > 10%, acute attacks | Samples | 1/21 (4.8%) | 3/62 (4.8%)§ |
| IgG-IF > 10%, acute MY | Samples | 1/12 (8.3%) | 1/23 (4.3%) |
| IgG-IF > 10%, acute ON | Samples | 0/6 (0%) | 2/33 (6.1%) |
| IgG-IF > 10%, acute BRAIN | Samples | 0/3 (0%) | 0/5 (0%) |
| QAlb > Qlim(Alb), acute attacks | Samples | 12/21 (57.1%) | 30/66 (45.5%)§ |
| QAlb > Qlim(Alb), acute MY | Samples | 8/12 (66.7%) | 14/24 (58.3%) |
| QAlb > Qlim(Alb), acute ON | Samples | 2/6 (33.3%) | 13/36 (36.1%) |
| QAlb > Qlim(Alb), acute BRAIN | Samples | 2/3 (66.7%) | 2/5 (40%) |
| CSF TP elevated, acute attacks | Samples | 15/24 (62.5%) | 27/68 (39.7%)§ |
| CSF TP elevated, acute MY | Samples | 9/12 (75%) | 12/25 (48%) |
| CSF TP elevated, acute ON | Samples | 4/9 (44.4%) | 11/37 (29.7%) |
| CSF TP elevated, acute BRAIN | Samples | 2/3 (66.7%) | 4/5 (80%) |
| CSF l-lactate elevated, acute attacks | Samples | 7/18 (38.9%) | 8/46 (17.4%)§ |
| CSF l-lactate elevated, acute MY | Samples | 6/10 (60%) | 4/16 (25%) |
| CSF l-lactate elevated, acute ON | Samples | 1/6 (16.7%) | 4/29 (13.8%) |
| CSF l-lactate elevated, acute BRAIN | Samples | 0/2 (0%) | 0/1 (0%) |
| Time since attack onset, acute LPs | Days | 5 (0-31) | 9.5 (0-34) |
To control for differences in the number of follow-up samples available per patient, only the first LP performed during each acute event was considered
IgG-IF intrathecal IgG fraction; OCB oligoclonal bands; QAlb CSF/serum albumin quotient; TP total protein
§p = n.s.