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. 2020 Sep 2;10(9):e038187. doi: 10.1136/bmjopen-2020-038187

Table 1.

Characteristics of pregnant women in the study cohort (n=2630)

Characteristic Total Total GWG
Below
(n=392)
Average
(n=1842)
Above
(n=396)
P value
Maternal age (year), mean±SD 29.4±3.6 29.9±3.8 29.4±3.5 28.5±3.6 <0.0001
Maternal age ≥35 years, n (%) 241 (9.2) 51 (13) 169 (9.2) 21 (5.3)  0.0002
Nulliparous, n (%) 2216 (84.3) 325 (82.9) 1532 (83.2) 359 (90.7)  0.0027
Education, university degree and above, n (%) 2404 (91.5) 362 (92.6) 1702 (92.5) 340 (85.7)  0.0007
ART, n (%) 55 (2.1) 9 (2.3) 37 (2) 9 (2.3)  0.9834
Tobacco smoking, n (%) 72 (2.7) 7 (1.8) 41 (2.2) 24 (6.1) <0.0001
Alcohol use, n (%) 338 (12.9) 52 (13.3) 240 (13) 46 (11.6)  0.7221
Prepregnancy BMI (kg/m2), mean±SD 21.3±3.0 21.7±3.1 21.2±3.0 21.5±2.9  0.0139
Prepregnancy BMI categories, n (%)
 Underweight (<18.5 kg/m2) 396 (15.1) 54 (13.8) 292 (15.9) 50 (12.6)  0.7530
 Normal weight (18.5–24.9 kg/m2) 1980 (75.3) 298 (76) 1372 (74.5) 310 (78.3)
 Overweight and obese (≥25 kg/m2) 254 (9.7) 40 (10.2) 178 (9.7) 36 (9.1)
 Gestational age at the first prenatal visit (week), median (IQR) 15 (3) 14 (3) 15 (3) 15 (3)  0.1986
GWG in early pregnancy by BMI categories (kg), mean±SD
 All women 2.2±2.9 −0.2±2.8 2.1±2.2 4.9±3.2 <0.0001
 Underweight (<18.5 kg/m2) 2.5±2.4 0.9±1.9 2.4±2.0 4.8±3.0 <0.0001
 Normal weight (18.5–24.9 kg/m2) 2.3±2.8 0.0±2.8 2.2±2.2 4.9±3.1 <0.0001
 Overweight and obese (≥25 kg/m2) 1.4±3.6 −2.2±3.3 1.5±2.6 4.7±4.4 <0.0001
GWG in late pregnancy by BMI categories (kg), mean±SD
 All women 13.0±3.5 8.2±3.0 12.6±2.9 17.8±3.6 <0.0001
 Underweight (<18.5 kg/m2) 13.0±3.5 8.9±1.9 12.8±2.5 18.2±3.8 <0.0001
 Normal weight (18.5–24.9 kg/m2) 12.9±4.0 8.4±3.0 12.8±2.8 17.8±3.6 <0.0001
 Overweight and obese (≥25 kg/m2) 11.0±4.9 5.8±3.3 10.8±3.8 17.4±3.8 <0.0001
GWG in whole pregnancy by BMI categories (kg), mean±SD
 All women 15.0±4.9 8.1±2.6 14.8±2.7 22.7±2.9 <0.0001
 Underweight (<18.5 kg/m2) 15.4±4.2 9.7±1.6 15.2±2.3 23.1±3.0 <0.0001
 Normal weight (18.5–24.9 kg/m2) 15.2±4.7 8.4±2.1 15.0±2.5 22.7±2.8 <0.0001
 Overweight and obese (≥25 kg/m2) 12.3±6.1 3.7±2.4 12.3±3.7 22.0±3.6 <0.0001
Gestational age at delivery (week), median (IQR) 39 (2) 39 (2) 39 (2) 39 (2)  0.0793
Birth weight (g), mean±SD 3376±450 3238±422 3370±438 3540±480 <0.0001
Male infant, n (%) 1334 (51.4) 194 (50.4) 945 (52) 195 (49.5)  0.7951

ART, assisted reproductive technology; BMI, body mass index; GWG, gestational weight gain.