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. 2020 Jan 13;41(5):661–669. doi: 10.1038/s41401-019-0325-6

Fig. 4. IMB-S7 suppresses the promoter activity of ITGAV.

Fig. 4

a LX2 cells were transfected with pGL4.20–2297 plasmid for 24 h, followed by incubation with IMB-S7 (0.2 mM) for another 24 h, and the ITGAV promoter activity was determined by the dual luciferase reporter assay. The data are expressed as the mean ± SD, **P < 0.01 compared with the pGL4.20 group; #P < 0.05 compared with the pGL4.20–2297 group. b LX2 cells were transfected with pGL4.20–2297 and different truncations (pGL4.20–1295, pGL4.20–796, pGL4.20–309, and pGL4.20–16) for 24 h, followed by IMB-S7 (0.2 mM) incubation for 24 h, and the activity of different promoters was determined by the dual luciferase reporter assay. Data are shown as a fold-induction relative to the pGL4.20 group. The data are expressed as the mean ± SD, *P < 0.05 compared with the corresponding DMSO group.