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. 2020 Jul 3;9:e56427. doi: 10.7554/eLife.56427

Appendix 1—scheme 4. Reductive aminoquinoline removal and final steps in the synthesis of I-(–)-paroxetine 3.

Appendix 1—scheme 4.

(a) AQ removal on enantiomerically pure trans-piperidine (–)-S3b (0.2 mmol, one equiv). (b) AQ removal on enantiomerically pure trans-piperidine (+)−7b (1.0 mmol, one equiv) and final steps in the synthesis of I-(–)-paroxetine 3.