Table 1.
Characteristics of three groups
| Olanzapine | Risperidone | Aripiprazole | Overall | P value | |
|---|---|---|---|---|---|
| n = 144 | n = 160 | n = 69 | n = 373 | ||
| Age (year) | 36.4 ± 14.9 | 41.0 ± 13.5 | 32.1 ± 12.3 | 38.0 ± 14.2 | 0.000 |
| Sex | |||||
| Male n (%) | 81 (56.3) | 74 (46.3) | 43 (62.3) | 198 (53.1) | 0.051 |
| BMI | 22.5 ± 4.0 | 22.9 ± 4.0 | 23.5 ± 4.3 | 22.9 ± 3.9 | 0.281 |
| Weight (kg) | 61.8 ± 11.0 | 64.3 ± 11.7 | 63.6 ± 13.0 | 63.1 ± 11.7 | 0.224 |
| Marital status | |||||
| Single n (%) | 82 (56.9) | 97 (60.6) | 36 (52.2) | 215 (57.6) | 0.417 |
| Married n (%) | 55 (38.2) | 59 (36.9) | 32 (46.4) | 146 (39.1) | − |
| Divorced or widowed n (%) | 7 (4.9) | 4 (2.5) | 1 (1.4) | 12 (3.2) | − |
| Occupation | |||||
| Employed n (%) | 56 (38.9) | 59 (36) | 40 (58.0) | 155 (41.6) | 0.009 |
| Unemployed n (%) | 88 (61.1) | 101 (63.1) | 29 (42.0) | − | − |
| Age at initial onset (year) | 26.9 ± 10.0 | 27.9 ± 9.7 | 25.7 ± 9.9 | 27.1 ± 9.8 | 0.275 |
| Illness duration (year) | 9.5 ± 12.3 | 13.1 ± 11.6 | 6.4 ± 7.4 | 10.4 ± 11.5 | 0.000 |
| Course (month) | 153.6 ± 305.8 | 24.9 ± 46.8 | 15.5 ± 22.1 | 72.9. ± 202.7 | 0.000 |
| Episode | |||||
| First episode n (%) | 49 (34.0) | 35 (21.9) | 20 (29.0) | 104 (27.9) | 0.060 |
| Onset frequency | 3.1 ± 3.1 | 3.4 ± 2.7 | 2.6 ± 2.0 | 3.1 ± 2.7 | 0.109 |
| Family history | |||||
| Positive (%) | 43 (29.1) | 32 (19.0) | 9 (12.2) | 84 (22.5) | 0.021 |
| PANSS score at baseline | |||||
| Total score | 69.5 ± 20.0 | 72.0 ± 22.6 | 64.2 ± 20.2 | 69.6 ± 21.3 | 0.038 |
| Positive score | 16.8 ± 6.8 | 17.4 ± 8.1 | 14.6 ± 6.2 | 16.7 ± 7.4 | 0.027 |
| Negative score | 18.1 ± 6.4 | 19.8 ± 7.4 | 17.0 ± 7.5 | 18.6 ± 7.1 | 0.013 |
| General psychopathology | 34.5 ± 11.1 | 34.8 ± 11.0 | 32.6 ± 10.3 | 34.3 ± 10.9 | 0.356 |
| PSP score at baseline | 50.8 ± 15.0 | 53.0 ± 15.2 | 58.0 ± 16.8 | 53.1 ± 15.6 | 0.007 |
Comparisons of continuous variables among groups were completed by using ANOVA or Kruskal–Wallis H