Table 2.
Effects of AB38b on kidney function of diabetic rats
| Groups (n = 6) | Fasting blood glucose (mmol/L) | Body weights (g) | Kidney index (g/kg) |
|---|---|---|---|
| N | 7.22 ± 0.56 | 30.65 ± 0.85 | 10.70 ± 0.56 |
| DN | 23.28 ± 2.43** | 23.73 ± 1.23** | 15.28 ± 1.24** |
| DN + AB38bL | 21.27 ± 1.66 | 24.38 ± 0.87 | 13.99 ± 0.48 |
| DN + AB38bM | 18.80 ± 2.74 | 25.57 ± 1.36 | 12.64 ± 0.44 |
| DN + AB38bH | 14.32 ± 3.13# | 24.94 ± 1.78 | 12.45 ± 0.39# |
| DN + Res | 15.23 ± 6.44 | 25.08 ± 1.49 | 13.35 ± 1.32 |
| N + AB38bH | 6.93 ± 0.54 | 29.91 ± 0.49 | 11.07 ± 0.71 |
N control group, DN the model group, DN + AB38bL low-dose group (AB38b of 10 mg/kg), DN + AB38bM medium-dose group (AB38b of 20 mg/kg), DN + AB38bH high-dose group (AB38b of 40 mg/kg), DN + Res positive control groups (resveratrol of 40 mg/kg), N + AB38bH control group + AB38b of 40 mg/kg
Data are expressed as the mean ± SD, n = 6. **P < 0.01 vs. N; #P < 0.05 vs. DN