Fig. 2.

ICS II suppressed inflammatory factors in astrocytes after LPS insult. Astrocytes were pretreated with or without ICS II (5, 10, and 20 μM) or DXMS (1 μM) for 1 h followed by LPS (1 μg/mL) for another 24 h. a TNF-α level (n = 5). b IL-1β level (n = 5). c Production of NO (n = 5). d Representative Western blot bands for iNOS and COX-2 proteins. e Quantitation of iNOS protein (n = 3). f Quantitation of COX-2 protein (n = 3). ^**P < 0.01 versus control group; ^#P < 0.05, ^##P < 0.01 versus LPS group