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. 2020 Jan 14;41(6):800–812. doi: 10.1038/s41401-019-0337-2

Fig. 1. The effects of IgD-Fc-Ig on paw swelling, AI, SJC, weight, paw volume, thymus/spleen indices, and T/B cell proliferation in CIA rats.

Fig. 1

a The effects of IgD-Fc-Ig on paw swelling in CIA rats during different inflammation stages. b The paw swelling volume in CIA rats and the effects of IgD-Fc-Ig was observed. c The AI of CIA rats was assessed, and the effects of IgD-Fc-Ig were assessed. d The SJC of CIA rats was observed, and the effects of IgD-Fc-Ig were observed. e The weight of CIA rats was observed, and the effects of IgD-Fc-Ig were observed. f The effects of IgD-Fc-Ig on the thymus and spleen indices in CIA rats. g The effects of IgD-Fc-Ig on the proliferation of T and B cells in CIA rats. *P < 0.05, **P < 0.01 vs Normal; #P < 0.05 vs CIA; $P < 0.05 vs IgD-Fc-Ig (9 mg/kg) (n = 10).