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a The percentages of Th17 and Treg cells in the spleen were observed by flow cytometry. b Bar graphs show the percentages of CD4+IL-17+ Th17 and CD4+CD25+Foxp3+ Treg cells. c The percentages of Th1 and Th2 cells in the spleen were observed by flow cytometry. d Bar graphs show the percentages of CD4+IFN-γ+ Th1 and CD4+IL-4+ Th2 cells. **P < 0.01 vs Normal; #P < 0.05, ##P < 0.01 vs CIA (n = 10).
