Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jul 20;48(15):8490–8508. doi: 10.1093/nar/gkaa597

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 7. — Model for pol IV extending D loops. Double-strand breaks are processed by the RecBCD helicase-nuclease multiprotein complex. RecBCD resects breaks and loads RecA on the single-stranded DNA regions, forming RecA* filaments. RecA* filaments are competent to induce the SOS response while undergoing homology search. Once a homologous sequence is found in the genome, a D loop can form which can be extended by certain DNA polymerases. Pol IV, for instance, can participate in recombination reactions following RecBCD activity.