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. 2020 Jul 28;48(15):8243–8254. doi: 10.1093/nar/gkaa630

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© The Author(s) 2020. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 5. — Modulation of PHO lncRNA termination can impact PHO mRNA repression. (A) Precocious termination of lncRNA synthesis upstream of the mRNA promoter can result in de-repression of mRNA transcription. (B) Decreased termination of lncRNA synthesis can increase interference with the mRNA promoter and hyper-repress mRNA expression. See text for discussion.