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. 2020 Jul 7;48(15):8782–8795. doi: 10.1093/nar/gkaa578

Figure 4.

Figure 4.

Important residues for ATP coordination of rnGLD-2. (A−C) Comparison between rnGLD-2 and other PAPs at adenosine nucleotide binding site. Residues of Bos taurus (bt)PAPα (PDB code: 1f5a, A), Saccharomyces cerevisiae (sc)PAP (PDB code: 2q66, B) and Gallus gallus mitochondria (ggMT)PAP (PDB code: 5a30, C) involved in binding 3′-dATP, ATP and ATPγS are individually superimposed with corresponding residues of rnGLD-2. (D) PAP activity of rnGLD-2 with mutations regarding the residues potentially involved in ATP coordination as shown in A−C.