Figure 2.
Patients with higher expression of HDAC3 exhibited earlier occurrence of brain metastasis (BM), and patients with BM have higher expression of HDAC3 than those without BM. (a–b) Brain metastasis‐free survival (BMF) curves of 139 IDC patients with different cytoplasmic HDAC3 (a) (
) HDAC3 C‐low (
) HDAC3 C‐high (
) HDAC3 C‐low‐censored (
) HDAC3 C‐high‐censored, and nuclear HDAC3 (b) levels (
) HDAC3 N‐low (
) HDAC3 N‐high (
) HDAC3 N‐low‐censored (
) HDAC3 N‐high‐censored. P‐values of the Kaplan‐Meier plots in (a–b) were calculated by log‐rank tests in SPSS. (c–d) Cytoplasmic HDAC3 (c); and nuclear HDAC3 (d) IHC scores of IDC patients with BM (n = 41) and without BM (n = 98) were compared quantitatively and are shown as the mean ± SD visually. P‐values of (c–d) were calculated by unpaired t‐test with Welch's correction. *
P < 0.05.