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Effect of mAb NJ001 on downstream gene expression. (a) RT‐qPCR analyses were used to validate TIMP‐3 and MMP‐7 expression. Data are expressed as the means ± s.d. *P < 0.001, compared with 0 ng/μl NJ001. (b) Western blots confirmed TIMP‐3 expression regulated by mAb NJ001 in SPC‐A1 cells. GAPDH was used as an internal control. Lower panel: relevant band densitometry analysis.
