Table 2. Improved Diagnostic Accuracy Achieved by Combining Detection of MTBK_24820-Specific Immune Responses.
Antigen | Group | Analyte | Sensitivity (%) | Specificity (%) |
---|---|---|---|---|
MTBK_24820 | Active TB vs. control | IL-6 | 23.1 | 95.4 |
IL-6+IFN-α | 38.5 | |||
IL-6+IFN-α+CXCL10 | 65.3 | |||
Active TB vs. LTBI | IFN-α | 25.0 | 100.0 | |
IFN-α+CXCL10 | 63.5 |
TB, tuberculosis; LTBI, latent TB infection; IFN, interferon; IL, interleukin; CXCL10, C-X-C motif chemokine.