. 2019 May 4;26(4):2023–2033. doi: 10.1007/s12253-019-00663-8

Table 1.

Classification of histone methyltransferases and demethyltransferases

Class			Members
HMTs	PRMTs	Type I	PRM1, PRM3, PMT1/HMT, PRMT4/CAMR1
	PRMTs	Type II	PRMT5
	HKMTs	Type I	G9a, EZH2, Suv39h1, Suv39h2, SET1, SET2, KMT2A
	HKMTs	Type II	DOTL1
HDMs	LSD1, UTX, JMJD3, JMJD1A

Adapted from Ref. [23]

PRMTs type I: mono-methylarginine and asymmetric dimethylargine; PRMTs type II: mono-methylarginine and symmeric dimethylarginine; HKMTs type I: lysine-specific SET histone transferases; HMTs type II: without lysine SET histone transferases