Table 1.
Clinical data of study groups
| Survival study | TMA study | Primary culture study | ||||
|---|---|---|---|---|---|---|
| Number of cases | 55 | 58 | 17 | |||
| Median age (years) | 47 (25–77) | 45 (31–71) | 51(36–70) | |||
| Histology | Number | % | Number | % | Number | % |
| Adenosquamous carcinoma | 1 | 1.8 | 5 | 8.6 | 1 | 5.9 |
| Adenocarcinoma | 0 | 0.0 | 7 | 12.1 | 1 | 5.9 |
| Squamous cell carcinoma | 54 | 98.2 | 43 | 74.1 | 15 | 88.2 |
| Dysplasia | 0 | 0.0 | 1 | 1.7 | 0 | 0.0 |
| No tumor | 0 | 0.0 | 2 | 3.4 | 0 | 0.0 |
| FIGO Stage | ||||||
| IA | 2 | 3.6 | 1 | 1.7 | - | - |
| IB | 15 | 27.3 | 16 | 27.6 | 1 | 5.9 |
| IIA | 12 | 21.8 | 10 | 17.2 | 1 | 5.9 |
| IIB | 23 | 41.8 | 14 | 24.1 | - | - |
| IIIB | 3 | 5.5 | - | - | - | - |
| No data | 0 | 0.0 | 17 | 29.3 | 15 | 88.2 |
| Grade | ||||||
| 1 | 19 | 34.5 | 13 | 22.4 | - | - |
| 2 | 30 | 54.5 | 23 | 39.7 | - | - |
| 3 | 6 | 10.9 | 2 | 3.4 | - | - |
| No data | 0 | 0.0 | 20 | 34.5 | 17 | 100.0 |
| Metastasis | 22 | 40.0 | 27 | 46.6 | 7 | 41.2 |
| HPV status | ||||||
| Only HPV16 | 27 | 49.1 | 17 | 29.3 | - | - |
| Only HPV18 | 2 | 3.6 | 2 | 3.4 | - | - |
| Only HPV33 | 0 | 0.0 | 0 | 0.0 | - | - |
| HPV16 + 18 | 12 | 21.8 | 5 | 8.6 | - | - |
| HPV16 + 33 | 7 | 12.7 | 1 | 1.7 | - | - |
| HPV18 + 33 | 1 | 1.8 | 0 | 0.0 | - | - |
| HPV16 + 18 + 33 | 5 | 9.1 | 3 | 5.2 | - | - |
| HPV negative | 1 | 1.8 | 8 | 13.8 | - | - |
| No data | 0 | 0.0 | 22 | 37.9 | 17 | 100.0 |
| No survival data | 4 | 7.3 | - | - | - | - |