Table 5.

Change in laboratory findings during the study.

Laboratory test	GS-3K8 group (n = 14)		GINST group (n = 15)		Placebo group (n = 15)
	Baseline	12 weeks	Baseline	12 weeks	Baseline	12 weeks
Hematology
WBC	5.72 ± 1.30	5.27 ± 0.98	5.36 ± 1.09	4.71 ± 0.99	4.70 ± 0.87	4.60 ± 1.46
Hemoglobin	13.87 ± 1.16	13.68 ± 1.14	13.67 ± 1.07	13.93 ± 0.98	13.53 ± 0.86	13.62 ± 0.70
Platelets	269.27 ± 58.97	268.14 ± 55.38	255.80 ± 49.36	256.73 ± 38.96	248.47 ± 37.90	249.73 ± 54.23
Chemistry
ALP	80.73 ± 16.54	87.57 ± 21.67	68.00 ± 19.49	68.47 ± 17.60	62.80 ± 14.96	65.87 ± 18.15
GGT	24.80 ± 26.43	23.07 ± 19.03	17.93 ± 16.33	16.33 ± 6.11	15.93 ± 4.06	14.67 ± 3.02
AST	23.67 ± 4.05	27.64 ± 8.74	26.73 ± 6.98	24.20 ± 4.04	25.27 ± 5.22	24.93 ± 4.30
ALT	19.00 ± 5.36	23.43 ± 8.40	23.40 ± 11.26	20.67 ± 6.99	22.27 ± 11.62	21.60 ± 6.96
Total bilirubin	0.81 ± 0.23	0.79 ± 0.17	0.82 ± 0.20	0.82 ± 0.33	0.88 ± 0.25	0.80 ± 0.26
Total protein	7.63 ± 0.33	7.53 ± 0.38	7.21 ± 0.32	7.38 ± 0.36	7.29 ± 0.34	7.33 ± 0.46
Albumin	4.44 ± 0.14	4.38 ± 0.17	4.35 ± 0.20	4.43 ± 0.21	4.31 ± 0.18	4.39 ± 0.22
BUN	14.67 ± 4.37	14.86 ± 4.04	13.00 ± 2.39	13.73 ± 2.52	12.13 ± 3.20	13.40 ± 4.07
Creatinine	0.64 ± 0.14	0.58 ± 0.13	0.61 ± 0.20	0.59 ± 0.18	0.56 ± 0.09	0.54 ± 0.05
Total cholesterol	188.73 ± 34.17	193.07 ± 28.24	203.93 ± 33.84	199.80 ± 27.02	187.40 ± 24.16	183.20 ± 21.99
Triglycerides	126.33 ± 58.08	109.29 ± 36.59	118.93 ± 47.62	123.13 ± 41.95	100.80 ± 36.28	99.07 ± 35.78
Glucose	86.33 ± 5.38	84.07 ± 6.89	88.67 ± 8.68	84.33 ± 6.78	86.33 ± 10.15	85.53 ± 6.14
Urinalysis
Specific gravity	1.02 ± 0.01	1.02 ± 0.01	1.02 ± 0.01	1.02 ± 0.01	1.02 ± 0.01	1.02 ± 0.01
pH	6.03 ± 0.92	5.86 ± 0.84	6.47 ± 1.04	6.43 ± 0.65	6.37 ± 0.92	6.13 ± 0.93

All values are presented as mean ± standard deviation.

ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate transaminase; BUN, blood urea nitrogen; GGT, gamma-glutamyltransferase; WBC, white blood cell.