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. 2020 Aug 21;8:820. doi: 10.3389/fcell.2020.00820

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Copyright © 2020 Xiao, Yao, Wang, Tian, Wang, Gu, Li, Zheng and Wu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The administration of FGLmx or FGLmx/Taxol reduced demyelination. (A–C) Histological assessment of transverse sections using LFB staining at the lesion epicenter. (A1–C1) Higher magnification micrographs of the posterior horn. The scale bar represents 100 μm. (D) Quantification of the demyelination area in the posterior horn of the lesion epicenter (± SEM). The IOD of the residual myelin sheath was higher in the FGLmx and FGLmx/Taxol groups than in the control group. The scale bar represents 500 μm in (A–C) and 100 μm in (A1,B1,C1). ^#P < 0.05 compared with the other two groups; *P < 0.05 compared with the control group.