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. 2020 Sep 3;10:14525. doi: 10.1038/s41598-020-71371-6

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Alpha diversity analysis between acute KD children, non-acute KD children and healthy controls. (A) Rarefaction curve and shannon index curve (B) were used to estimate the sequencing depth (at a 97% similarity level) of the fecal microbiota between three groups. ACE index (C) revealed that non-acute KD children have higher bacterial richness than the acute KD children and healthy controls. Simpson index (D) revealed that acute KD children have a lower biodiversity than the non-acute KD children and healthy controls. K acute KD children, F non-acute KD children, N healthy controls.