Fig. 5.
Voltage dependence of cocaine inhibition in α3β4 nAChR-mediated current a. Typical traces show the whole-cell current responses of SH-SY5Y α3β4 cells to 20 µM nicotine alone (black trace) or coapplied with 1.5 µM cocaine (gray trace) at the indicated VH. b Bar graph comparing the effects of cocaine during exposure to nicotine at the indicated VH (n = 8), ***P < 0.001 (baseline vs. cocaine exposure at a VH of −60 mV)