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. 2019 Dec 17;41(5):650–660. doi: 10.1038/s41401-019-0328-3

Fig. 5. AMI and IMI ameliorated abnormal metabolism in HFD-fed rats.

Fig. 5

Male Sprague–Dawley rats were fed a HFD to establish a rat model of leptin resistance. HFD-fed rats were treated with AMI (10 mg· kg−1 per day, i.p.) and IMI (10 mg· kg−1 per day, i.p.) for 2 weeks. Summarized data showing the role of AMI and IMI on body weight (a), weight gain (b), T-CHO (c), TG (d), LDL (e), NEFA (f), HDL (g), and leptin levels (h), ASM activity (i), eNOS activity (j) and NO release (k) in the serum. The data are the means ± SEMs from six experiments. *P < 0.05 vs. control (Ctrl); #P < 0.05 vs. HFD-fed rats.