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. 2019 Dec 17;41(5):650–660. doi: 10.1038/s41401-019-0328-3

Fig. 6. AMI and IMI relieved endothelial leptin resistance in HFD-fed rats.

Fig. 6

Representative immunohistochemical images showing the role of AMI and IMI on the levels of Ob-Rb, p-STAT3-Tyr705, SOCS3, and ASM in the aorta (a, scale bar = 100 μm). Representative immunofluorescence images showing the colocalization of ASM or SOCS3 with vWF (b, scale bar = 100 μm) in the vascular endothelium. The calculated colocalization efficiency is shown in Fig. 6c, d. The data are the means ± SEMs from six experiments. *P < 0.05 vs. control (Ctrl); #P < 0.05 vs. HFD-fed rats.