Table 1.
Correlation analyses between IGF-II, IGFBP-5 and other variables and regression with height and BMI
| Variable | IGFBP-5 | Free IGF-Ia | Total IGF-Ia | Intact IGFBP-3 | Total IGFBP-3 | PAPP-A2a | Free/total IGF-Ia | Height z-score | BMI z-score | |
|---|---|---|---|---|---|---|---|---|---|---|
| Males | ||||||||||
| IGF-II (N = 405) | r P value | −0.10 (0.05) | −0.15 (0.003) | 0.07 (0.17) | 0.17 (0.0006) | 0.53 (<0.0001) | 0.02 (0.65) | −0.19 (0.0002) | −0.015 (0.77) | −0.007 (0.89) |
| IGFBP-5 (N = 405) | r P value | 0.39 (<0.0001) | 0.44 (<0.0001) | 0.32 (<0.0001) | 0.008 (0.87) | −0.14 (0.004) | −0.009 (0.86) | 0.12 (0.02) | −0.02 (0.71) | |
| Females | ||||||||||
| IGF-II (N = 431) | r P value | 0.07 (0.13) | 0.06 (0.22) | −0.05 (0.27) | 0.04 (0.57) | 0.51 (<0.0001) | 0.12 (0.02) | 0.10 (0.03) | −0.028 (0.56) | −0.045 (0.35) |
| IGFBP-5 (N = 431) | r P value | 0.41 (<0.0001) | 0.51 (<0.0001) | 0.32 (<0.0001) | 0.18 (0.0001) | −0.10 (0.04) | −0.04 (0.37) | 0.04 (0.37) | −0.029 (0.55) |
aThe natural log-transformation was used for statistical analysis of free and total IGF-I, PAPP-A2 and free/total IGF-I ratio.
Note: Bivariate Pearson correlation analyses were performed. The r means the Pearson correlation coefficient. A P-value less than 0.05 was considered statistically significant.