Fig. 3.

Organizing pneumonia following dual ipilimumab/nivolumab therapy. Progressive dyspnea and dry cough developed 3 weeks following cycle 3 of azacitadine plus nivolumab and ipilimumab for myelodysplastic syndrome. A chest CT demonstrated multifocal consolidative and ground glass opacities involving the right upper lobe (a) and bilateral lower lobes (b). Bronchoalveolar lavage fluid was culture negative. Prominent intraluminal plugs of inflammatory debris within the small airways were seen on lung biopsy, consistent with organizing pneumonia caused by combined Nivolumab/Ipilimumab therapy