FIGURE 6.

Sox9 expressing cells in the MES and the palatal osteogenic centers. Upper panels: Fluorescent immunohistochemical-stained coronal palatal sections for Sox9-activity (red), representative for the wt E15 fetuses and HO-2 KO E15 fetuses. Middle panels: Strong Sox9 expressing cells (red) were found in the remnants of the MES. Green panels: Sox9 expressing mesenchymal cells were present in the osteogenic centers at the oral side of the forming nasal septum, and also in the cartilage of the nasal septum. Red panels: The osteogenic centers in the lateral parts of the fusing palate demonstrated clusters of strong Sox9 expressing cells.