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. 2020 Aug 21;8:772. doi: 10.3389/fbioe.2020.00772

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Copyright © 2020 Garcia, Thompson, Giannone, Dash, Maranas and Trinh.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Metabolic map visualization for (A) redox and hydrogenases pathway, (B) pyruvate node that links glycolysis, incomplete Krebs cycle, anapleurotic pathway, and fermentative pathway, and (C) sulfur metabolism using the Escher tool. Values next to reaction labels correspond to proteomics fold change between the ΔhydGΔech and wild-type strains only for the 70 consistent reactions identified by using the FC-based omics integration protocol (section 2.5). The labels of extracellular metabolites are appended with “_e.” Reactions marked with a red cross are deleted in ΔhydGΔech.