Table 2.
List of all Metabolites Altered by ETOM (100 μM) Treatment with Regard to Relative Amounts for HK157
| TCA Cycle | Pentose Phosphate | Nucleotide Metabolism | Amino Acid Metabolism | Fatty Acid/Lipid Metabolism | Currency | Other |
|---|---|---|---|---|---|---|
| α-Keto glutarate | Cystathionine | Adenosine triphosphate | L-Alanine | O-Acetylcarnitine | Adenosine triphosphate | D-Glucosamine 6-phosphate |
| Citrate | α-D-Glucose 6-phosphate | Deoxyadenosine triphosphate | L-Proline | Phosphocholine | Creatine | 4-Hydroxyphenyllactate |
| Fumarate | Inosine monophosphatea | Cytidine diphosphate | L-Serine | Phosphoethanolamine | Reduced nicotinamide adenine dinucleotide | 4-OH Phenyl acetic acid |
| Aconitate | Ribose 5-phosphate | Cytidine triphosphate | L-Threonine | Adenosine monophosphate/Adenosine triphosphate ratioa | L-Ascorbic acid | |
| L-Glutamine | Guanosine triphosphate | L-Citrulline | ||||
| L-Glutamate | Uridine triphosphate | 2-Methyl-propionyl-CoA | ||||
| Orotidine | ||||||
| Cytidinea | ||||||
| Cytosinea | ||||||
| Guanosinea |
Metabolites were measured by labeled 13C-palmitic acid using LC-MS analysis (p < 0.05 for all metabolites listed).
Indicates an increase with ETOM treatment.