. 2020 Aug 13;23(9):101453. doi: 10.1016/j.isci.2020.101453

Table 4.

List of all Metabolites Altered by ETOM (100 μM) Treatment with Regard to Relative Amounts for IDH1 Mutant HK252

TCA Cycle	Nucleotide Metabolism	Amino Acid Metabolism	Currency	Other
2-Hydroxyglutarate	Adenine^a	2-Methylpropanoyl-CoA	Acetyl-CoA	D-Fructose 1,6-bisphosphate
L-Glutamate	Deoxyadenine^a	Glycine	Creatine	α-D-Glucose 6-phosphate
	Guanosine monophosphate		Reduced nicotinamide adenine dinucleotide	D-Glucosamine 6-phosphate
	Inosine^a			Pantothenate
	Orotate^a			Sorbitol

Metabolites were measured by labeled ¹³C-palmitic acid using LC-MS analysis (p < 0.05 for all metabolites listed).

Indicates an increase with ETOM treatment.