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. 2020 Aug 21;8:1003. doi: 10.3389/fbioe.2020.01003

FIGURE 7.

FIGURE 7

The Sankey plot of the endogenous competitive network in three TME groups. The rectangle size of miRNA represents the number of DEGs and lncRNAs. Panel (A) represents the ceRNA network of differentially expressed miRNA, lncRNA, and genes in the TME-A versus TME-B. Panel (B) represents the ceRNA network of differentially expressed miRNA, lncRNA, and genes in the TME-A versus TME-C. Panel (C) represents the ceRNA network of differentially expressed miRNA, lncRNA, and genes in the TME-B versus TME-C. Panel (D) represents the correlation of differentially expressed miRNA and lncRNAs between TME-B and TME-C. The “Diff” is defined as the differential correlation in TME-B versus TME-C. Signal plot shows the degree of correlation. The P value is labeled with asterisks below signal plot (***P < 0.001, **P < 0.01, *P < 0.05). (E,F) The Kaplan–Meier survival analysis for differentially expressed lncRNAs in TME-B versus TME-C. Red (blue) line represents the survival probability of patients with sarcomas when the expression level of RNAs is high (low).