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. 2020 Sep 3;10:14531. doi: 10.1038/s41598-020-71475-z

Figure 6.

Figure 6

PKM2 and pPKM2 expression in WT mice and PFKFB2 KI mice with UUO and FAN. (A,C,E) Representative Western blots showing significantly increased expression of PKM2 and pPKM2 in WT and PFKFB2 KI mice with UUO, as determined by densitometry. There was a significant difference in expression of PKM2 but not pPKM2 between WT and PFKFB2 KI mice. (B,D,F) Representative Western blots showing no change in expression of PKM2 and pPKM2 in WT with FAN, as determined by densitometry. There was a difference in the PFKFB2 KI mice between control and FAN mice, but no difference when compared to WT mice. n = 6 mice per panel. *P < 0.05, **P < 0.01, ***P < 0.001. Mean + S.D.