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. 2020 Sep 3;10:14531. doi: 10.1038/s41598-020-71475-z

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Histochemical evaluation of renal fibrosis in WT and PFKFB2 KI mice with UUO and FAN. Representative images of Picro-Sirius Red stained kidney sections from WT and PFKFB2 KI mice with UUO (A) and FAN (B). Quantification of Picro-Sirius Red stained kidney sections showing increased staining in PFKFB2 KI mice with UUO compared to WT mice (C). There was no difference between WT and PFKFB2 KI mice with FAN (D). (n = 7 for all groups). ****P < 0.0001. Mean + S.D.