Table 5.
Toxicity evaluation in “IRT” vs “NIRT” groups (n = 80 patients), p < 0.05.
| Toxicity | Inguinal RT “IRT” 54/80 (%) |
No inguinal RT “NIRT” 26/80 (%) |
||
|---|---|---|---|---|
| G1–G2 | G3–G4 | G1–G2 | G3–G4 | |
| Perineal dermatitis | 30 (56) | 22 (41) | 12 (46) | 14 (54) |
| Inguinal dermatitis |
27 (50)* (p = 0.001)* |
9 (17)# (p = 0.03)# |
3 (12)* | 0# |
| Diarrhoea | 25 (46) | 3 (6) | 17 (65) | 2 (8) |
| Genito-urinary | 19 (35) | 1 (2) | 13 (50) | 0 |
| Vaginitis | 6/32 (19) | 0 | 5/16 (31) | 0 |
| Nausea/vomiting | 13 (24) | 0 | 3 (12) | 0 |
| Stomatitis | 4 (7) | 2 (4) | 3 (12) | 0 |
| Neutropenia | 10 (19) | 8 (15) | 5 (19) | 5 (19) |
IRT: inguinal RT; NIRT: non inguinal RT.
* Inguinal G1-G2 dermatitis “IRT” vs “NIRT”.
#Inguinal G3–G4 dermatitis “IRT” vs “NIRT”.