Figure 5.

Expression levels of apoptosis-related proteins determined using western blotting in the control, NC-inhibitor and miR-19a-inhibitor groups. (A) Expression of apoptosis-related proteins by western blotting and statistical analyses of the ratios of (B) Bcl-2/Bax and (C) cleaved caspase-3/caspase-3. Compared with those in the control group and NC-inhibitor group, the Bcl-2/Bax ratio was significantly decreased while the ratio of cleaved caspase-3/caspase-3 was significantly higher in the miR-19a-inhibitor group. **P<0.01 vs. the NC-inhibitor group. NC, negative control; Bcl-2, B-cell lymphoma-2; Bax, Bcl-2 associated X protein.