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. 2020 Aug 26;2020:8879448. doi: 10.1155/2020/8879448

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Copyright © 2020 Runhui Zheng et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fiberoptic bronchoscopy and PET/CT images. (a) Fiberoptic bronchoscopy revealed intratracheal mass in right main bronchi with complete right mainstem bronchus occlusion before treatment. (b) PET/CT image showing left hilum and mediastinal mass (41 × 87 × 76 mm, FDG uptake 20.6) with compression of the pulmonary artery, lower tracheal segment, bilateral main bronchi, and superior vena cava. (c) Right mainstem bronchus was completely occluded, and a tracheal stent was implanted. (d) Bronchus occlusion was significantly improved after treatment with PD-1 inhibitor and DNMTi/HDACi. (e) Restaging PET image showing dramatically shrinkage of hilum and mediastinal mass (16 × 15 mm, FDG uptake 8.0) after a triple combination treatment of DNMTi/HDACi plus PD-1 inhibitor.