Table 2.
Baseline demographic characteristics and outcome measures of patients.
| Parameters | Normotriglyceridaemia (N = 217) | Mild hypertriglyceriademia (N = 47) | Moderate-to-severe hypertriglyceriademia (N = 40) | Total (N = 304) | p value |
|---|---|---|---|---|---|
| Demographic data | |||||
| Age, mean (SD), years | 57.8 (20.4) | 41.2 (23.7) | 48.4 (15.0) | 56.07 (19.7) | 0.03∗ |
| 18–39, n (%) | 49 (22.6) | 9 (19.2) | 15 (37.5) | 73 (24.0) | |
| 40–59, n (%) | 62 (28.6) | 21 (44.7) | 15 (37.5) | 98 (32.2) | |
| 60–79, n (%) | 63 (29.0) | 13 (27.7) | 9 (22.5) | 85 (28.0) | |
| ≥80, n (%) | 43 (19.8) | 4 (8.5) | 1 (2.5) | 48 (15.8) | |
| Gender | 0.04∗ | ||||
| Male, n (%) | 103 (47.5) | 30 (63.8) | 24 (60.0) | 157 (51.6) | |
| Female, n (%) | 114 (52.5) | 17 (36.2) | 16 (40.0) | 147 (48.4) | |
| BMI (kg/m2) | 0.58 | ||||
| <30, n (%) | 137 (63.1) | 32 (68.1) | 25 (62.5) | 194 (63.8) | |
| ≥30, n (%) | 74 (34.1) | 13 (27.7) | 15 (37.5) | 102 (33.6) | |
| Unknown, n (%) | 6 (2.8) | 2 (4.3) | 0 | 8 (2.6) | |
| Smoking status | 0.06 | ||||
| Smoker, n (%) | 39 (18.0) | 12 (25.5) | 13 (32.5) | 64 (21.1) | |
| Non-smoker, n (%) | 174 (80.2) | 31 (66.0) | 27 (67.5) | 232 (76.3) | |
| Unknown, n (%) | 4 (1.8) | 4 (8.5) | 0 | 8 (2.6) | |
| Severity | |||||
| APACHE II score < 9 | 78 (35.9) | 20 (44.7) | 23 (57.5) | 121 (39.8%) | 0.07 |
| APACHE II score ≥ 9 | 92 (42.4) | 15 (31.9) | 8 (20.0) | 115 (37.8%) | |
| Unknown | 47 (21.7) | 12 (25.5) | 9 (22.5) | 68 (22.4%) | |
| Biochemistry | |||||
| Triglyceride concentration, median (interquartile range), mmol/L | 1 (0.8–1.2) | 1.9 (1.8–2.1) | 3.65 (2.4–5.9) | 1.2 (0.9–1.8) | <0.01∗ |
| C-reactive protein concentration, median (interquartile range), mg/L | 21.0 (6.0–122.0) | 23.5 (6.0–83.0) | 50.5 (19.0–114.0) | 24.5 (7.0–115.0) | 0.18 |
| White cell count, mean (SD), x10ˆ9 cells/L | 13.2 (5.4) | 13.96 (5.5) | 13.44 (5.6) | 13.3 (5.5) | 0.35 |
| APACHE II score, mean (SD) | 9.6 (4.6) | 8.4 (4.59) | 7.4 (3.05) | 9.1 (4.50) | 0.07 |
| Primary aetiology, n (%) | |||||
| Gallstones | 133 (61.3) | 19 (40.0) | 14 (35.0) | 166 (54.6) | <0.01∗ |
| Alcohol | 28 (12.9) | 14 (30.0) | 12 (30.0) | 54 (17.8) | <0.01∗ |
| Hypertriglyceridaemia | 0 | 14 (30.0) | 14 (35.0) | 28 (9.2) | <0.01∗ |
| Iatrogenic: post-ERCP or cholecystectomy | 6 (2.8) | 0 | 0 | 6 (2.0) | 0.30 |
| Abnormal bile duct | 4 (1.8) | 0 | 0 | 4 (1.3) | 0.45 |
| Idiopathic | 46 (21.2) | 0 | 0 | 46 (15.1) | 0.04∗ |
| Outcome | |||||
| Duration of stay, median (interquartile range), days | 4 (2.5–7.0) | 6 (3.0–11.0) | 5 (2.0–10.5) | 4 (2.0–8.0) | <0.01∗ |
| Critical care admission, n (%) | 16 (7.4) | 8 (17.0) | 9 (22.5) | 33 (10.9) | 0.01∗ |
| Hospital readmission, n (%) | 23 (10.6) | 6 (12.8) | 4 (10.0) | 33 (10.9) | 0.90 |
| Mortality, n (%) | 17 (7.8) | 2 (4.3) | 4 (10.0) | 23 (7.6) | 0.58 |
∗ indicates statistically significant differences (p < 0.05).