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. 2020 Aug 21;10:1628. doi: 10.3389/fonc.2020.01628

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Copyright © 2020 Niu, Yan, Guo, Wang, Zhao, Ren, Huang, Zhang, Yu and Liang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Immune cells infiltration analysis. (A) The distribution of 22 types of immune cells between primary and metastatic osteosarcoma tissues. (B) The difference of immune cells infiltration between primary and metastatic osteosarcoma tissues visualized by heatmap. (C) Violin plot visualizing the differentially infiltrated immune cells (P < 0.05). (D) PCA performed on all osteosarcoma tissues. The two principal components showed nothing significant variation. PCA, principal component analysis.